In Individuals rats skilled to self-administer oxycodone, administration of an immunoconjugate vaccine (Oxy-TT) diminished oxycodone concentrations in Mind by 50% and vaccination diminished the rat's oxycodone consumption and provided safety against the reinforcing effects of oxycodone. The exact neuronal pathways that cause opioid addiction and abuse want even more investigating. https://wockusa.com/product-category/codeine/